| Country | Player | Rank1 | Seed |
| CHI | Christian Garin | 22 | 1 |
| USA | John Isner | 25 | 2 |
| FRA | Adrian Mannarino | 34 | 3 |
| POL | Hubert Hurkacz | 35 | 4 |
| USA | Tommy Paul | 52 | 5 |
| USA | Sam Querrey | 56 | 6 |
| ESP | Pablo Andъjar | 59 | 7 |
| USA | Frances Tiafoe | 62 | 8 |
Tennis betting is a popular option at legal online sportsbooks. There are betting odds available for all of the ATP and WTA events, as well as for other top tours across the globe. Wagering interest tends to be the highest for the four majors, aka the “Grand Slam,” which consists of the Australian Open, French Open, US Open, and Wimbledon.