| Country | Player | Rank | Seed |
| RUS | Daniil Medvedev | 3 | 1 |
| GRE | Stefanos Tsitsipas | 6 | 2 |
| GER | Alexander Zverev | 7 | 3 |
| RUS | Andrey Rublev | 8 | 4 |
| ESP | Roberto Bautista Agut | 13 | 5 |
| BEL | David Goffin | 15 | 6 |
| CAN | Fйlix Auger-Aliassime | 19 | 7 |
| SUI | Stan Wawrinka | 20 | 8 |
Tennis betting is a popular option at legal online sportsbooks. There are betting odds available for all of the ATP and WTA events, as well as for other top tours across the globe. Wagering interest tends to be the highest for the four majors, aka the “Grand Slam,” which consists of the Australian Open, French Open, US Open, and Wimbledon.